Preisträger Medizinische Grundlagenforschung 1988 – 2012
| 2012 | Prof. Dr. H.C. Reinhardt | DNA Damage Activates a Spatially Distinct Late Cytoplasmic Cell-Cycle Checkpoint Network Controlled by MK2-Mediated RNA Stabilization |
| 2011 | Dr. Daniel N. Wilson | Interplay between the Ribosomal Tunnel, Nascent Chain, and Macrolides Influences Drug Inhibition
und Head swivel on the ribosome facilitates translocation by means of intra-subunit tRNA hybrid sites |
| 2010 | Prof. Dr. Veit Hornung | RIG-I-dependent sensing of poly (dA:dT) through the induction of an RNA polymerase III- transcribed RNA intermediate. |
| 2009 | Prof. Dr. Norbert Hübner | Soluble epoxide hydrolase is a susceptibility factor for heart failure in a rat model of human disease. |
| 2008 | Prof. Dr. Bernhard Nieswandt | An EF hand mutation in Stim1 causes premature platelet activation and bleeding in mice. Loss of talin1 in platelets abrogates integrin activation, platelet aggregation and thrombus formation in vitro and in vivo. |
| 2007 | PD Dr. Volker Heussler | Manipulation of Host Hepatocytes by the Malaria parasite for Delivery into Liver Sinusoids. |
| 2006 | Dr. Ann-Kristin Müller | Genetically modified Plasmodium parasites as a protective experimental malaria vaccine. Plasmodium liver stage developmental arrest by depletion of a protein at the parasite-host interface. |
| 2006 | Prof. Dr. Ivan Dikic | Ubiquitin-binding domains in Y-family polymerases regulate translesion synthesis. Ubiquitin-binding domains in Y-family polymerases regulate translesion synthesis |
| 2005 | PD Dr. med. Karl Rudolph | Telomere length is reset during early mammalian embryogenesis. Mitogen Stimulation Cooperates with Telomere Shortening To Activate DNA Damage Responses and Senescene Signaling. |
| 2004 | Dr. Michael Zeisberg | BMP-7 counteracts TGF-β1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury. Bone morphogenic protein-7 inhibits progression of chronic renal fibrosis associated with two genetic mouse models. |
| 2004 | Dr. Kirsten Lauber | Apoptotic Cells Induce Migration of Phagocytes via Caspase-3-Mediated Release of a Lipid Attraction Signal. |
| 2003 | Prof. Dr. Christian Weber | Deposition of platelet RANTES triggering monocyte recruitment requires P-selectin and is involved in neointima formation after arterial injury. JAM-1 is a ligand of the β2 integrin LFA-1 involved in transendothelial migration of leukocytes. |
| 2002 | Prof. Dr. Patrick Cramer | Structural Basis of Transcription: RNA Polymerase II at 2.8 Ångstrom Resolution. |
| 2001 | PD Dr. Elke Roeb | An MMP-9 mutant without gelatinolytic activity as a novel TIMP-1-antagonist. |
| 2000 | Dr. habil. Thomas Willnow | An Endocytic Pathway for Renal Uptake and Activation of the Steroid 25-(OH) Vitamin D3. |
| 1999 | Prof. Dr. Richard Kroczek | CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells. |
| 1999 | PD Dr. Rita Gerardy-Schahn | Die Bedeutung der Polysialinsäure für das Wachstum und Metastasierungsverhalten neuroendokriner und lymphoider Tumoren. |
| 1999 | PD Dr. Ortrud Steinlein | A Potassium Channel Mutation in Neonatal Human Epilepsy. |
| 1998 | Dr. Stefan Offermanns | Vascular System Defects and Impaired Cell Chemokinesis as a Result of Gα13 Deficiency. |
| 1997 | Prof. Dr. Dr. Manfred W. Kiliman | Mutations in the testis/liver isoform of the phosphoylase kinase γ subunit (PHKG2) cause autosomal liver glycogenosis in the gsd rat and in humans. |
| 1996 | Prof. Dr. Dietmar Vestweber | The E-selectin-ligand ESL-1 is a variant of a receptor for fibroblast growth factor. |
| 1995 | Dr. Ludwig Thierfelder | A familial hypertrophic cardiomyopathy locus maps to chromosome 15q2. |
| 1994 | Prof. Dr. Martin Krönke | Human 55-kDa receptor for tumor necrosis factor couples to signal transduction cascades. |
| 1993 | PD Dr. Peter Gierschik | sozyme-selective stimulation of phospholipase C-β2 by G-protein βγ-subunits. |
| 1992 | PD Dr. Klaus Ley | Endothelial, not hemodynamic differences are responsible for preferential leukocyte rolling in rat mesenteric venules. |
| 1991 | Prof. Dr. Stefan H. E. Kaufmann | T-Cells against a bacterial heat shock protein recognize stressed macrophages. |
| 1990 | Prof. Dr. Bernhard Fleischer | Stimulation von T-Lymphozyten durch
mikrobielle Exotoxine: Ein in der Evolution konservierter Mechanismus. |
| 1989 | Prof. Dr. Peter C. Weber PD Dr. Sven Fischer Dr. Clemens von Schacky |
zelluläre Funktionen. |
| 1988 | Prof. Dr. Wolfram H. Gerlich Dr. Klaus-Hinrich Heermann |
Wege zu einem optimalen Impfstoff gegen Hepatitis-B-Viren. |
| 1988 | Prof. Dr. Karl-G. Dorst | Entwicklung und Erprobung eines integrativen Behandlungsprogramms bei essentieller Hypertonie. |
Was ist eine klinische Studie?
